WIPI1 Blocking Peptide (N-term)

Background:
WD40 repeat proteins are key components of many essentialbiologic functions. They regulate the assembly of multiproteincomplexes by presenting a beta-propeller platform for simultaneousand reversible protein-protein interactions. Members of the WIPIsubfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladedpropeller structure and contain a conserved motif for interactionwith phospholipids (Proikas-Cezanne et al., 2004 [PubMed15602573]).

Other Names:
WD repeat domain phosphoinositide-interacting protein 1, WIPI-1, Atg18 protein homolog, WD40 repeat protein interacting with phosphoinositides of 49 kDa, WIPI 49 kDa, WIPI1, WIPI49

Target/Specificity:
The synthetic peptide sequence is selected from aa 47-59 of HUMAN WIPI1

Gene Name: WIPI1

Gene ID: 55062
Primary Accession: Q5MNZ9
Other Accession: Q8R3E3; NP_060453
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.