WISP3 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP6257a
Background:
Wisp2 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members contain four well-conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and the C-terminal cysteine knot-like (CT) domain. Human Wisp2 is 72% identical to the mouse Wisp2 protein. Wisp2 is abundantly expressed in bone tissue, and may play an important role in modulating bone turnover. Wisp2 expression in colon tumors is often reduced while the other two Wisp members (Wisp1 and 3) are overexpressed in these tumors.
Other Names:
WNT1-inducible-signaling pathway protein 3, WISP-3, CCN family member 6, WISP3, CCN6
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6257a was selected from the Center region of human WISP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CCN6 (HGNC:12771)
Gene ID: 8838
Primary Accession: O95389
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Wisp2 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members contain four well-conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and the C-terminal cysteine knot-like (CT) domain. Human Wisp2 is 72% identical to the mouse Wisp2 protein. Wisp2 is abundantly expressed in bone tissue, and may play an important role in modulating bone turnover. Wisp2 expression in colon tumors is often reduced while the other two Wisp members (Wisp1 and 3) are overexpressed in these tumors.
Other Names:
WNT1-inducible-signaling pathway protein 3, WISP-3, CCN family member 6, WISP3, CCN6
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6257a was selected from the Center region of human WISP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CCN6 (HGNC:12771)
Gene ID: 8838
Primary Accession: O95389
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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