WNK3 (PRKWNK3) Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP7054b
Background:
Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM]
Other Names:
Serine/threonine-protein kinase WNK3, Protein kinase lysine-deficient 3, Protein kinase with no lysine 3, WNK3, KIAA1566, PRKWNK3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7054b was selected from the C-term region of human PRKWNK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: WNK3 {ECO:0000303|PubMed:11571656, ECO:0000312|HGNC:HGNC:14543}
Gene ID: 65267
Primary Accession: Q9BYP7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM]
Other Names:
Serine/threonine-protein kinase WNK3, Protein kinase lysine-deficient 3, Protein kinase with no lysine 3, WNK3, KIAA1566, PRKWNK3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7054b was selected from the C-term region of human PRKWNK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: WNK3 {ECO:0000303|PubMed:11571656, ECO:0000312|HGNC:HGNC:14543}
Gene ID: 65267
Primary Accession: Q9BYP7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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