Wnt3 (clone 4F11-H1-F4), anti-transfected
€295.00
In stock
SKU
K000174M
Catalog Number: K000174M
Size: 100 μl
Other size: 50 μl
Isotype: Mouse lgG1
Applications: WB
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Size: 100 μl
Other size: 50 μl
Isotype: Mouse lgG1
Applications: WB
Request Manual
Questions? Contact us!
Background:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Synonyms: INT4, TETAMS
Cellular Location: Secreted extracellular matrix extracellular space
Immunogen:
Purified recombinant human Wnt3 protein fragments expressed in E.coli.
Gene Symbol: Wnt3
Gene ID: 7473
Swiss prot: P56703
Calculated MW: 40kDa
Recommended dilution:
WB 1:1000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Synonyms: INT4, TETAMS
Cellular Location: Secreted extracellular matrix extracellular space
Immunogen:
Purified recombinant human Wnt3 protein fragments expressed in E.coli.
Gene Symbol: Wnt3
Gene ID: 7473
Swiss prot: P56703
Calculated MW: 40kDa
Recommended dilution:
WB 1:1000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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