XIAP (BIRC4) Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP6125a
Background:
BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
Other Names:
E3 ubiquitin-protein ligase XIAP, 632-, Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP, XIAP, API3, BIRC4, IAP3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6125a was selected from the N-term region of human BIRC4 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: XIAP {ECO:0000303|PubMed:12121969, ECO:0000312|HGNC:HGNC:592}
Gene ID: 331
Primary Accession: P98170
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
Other Names:
E3 ubiquitin-protein ligase XIAP, 632-, Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked IAP, XIAP, API3, BIRC4, IAP3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6125a was selected from the N-term region of human BIRC4 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: XIAP {ECO:0000303|PubMed:12121969, ECO:0000312|HGNC:HGNC:592}
Gene ID: 331
Primary Accession: P98170
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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