XPC antibody (clone 6D11), anti-human
€435.00
In stock
SKU
AC-AT4551a
Catalog Number: AC-AT4551a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT4551a">Request Information
Background:
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Other Names:
DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125, XPC, XPCC
Antigen Type:
Recombinant Protein
Gene Name: XPC
Gene ID: 7508
NCBI Accession: NP_001139241.1;NP_004619.3
Primary Accession: Q01831
Other Accession: NM_004628
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Other Names:
DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125, XPC, XPCC
Antigen Type:
Recombinant Protein
Gene Name: XPC
Gene ID: 7508
NCBI Accession: NP_001139241.1;NP_004619.3
Primary Accession: Q01831
Other Accession: NM_004628
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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