XPC Blocking Peptide(N-term)
€363.00
In stock
SKU
AC-BP19709a
Background:
This gene encodes a component of the nucleotide excisionrepair (NER) pathway. There are multiple components involved in theNER pathway, including Xeroderma pigmentosum (XP) A-G and V,Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) groupA, etc. This component, XPC, plays an important role in the earlysteps of global genome NER, especially in damage recognition, opencomplex formation, and repair protein complex formation. Mutationsin this gene or some other NER components result in Xerodermapigmentosum, a rare autosomal recessive disorder characterized byincreased sensitivity to sunlight with the development ofcarcinomas at an early age. Alternatively spliced transcriptvariants have been found for this gene.
Other Names:
DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125, XPC, XPCC
Target/Specificity:
The synthetic peptide sequence is selected from aa 169-183 of HUMAN XPC
Gene Name: XPC
Gene ID: 7508
Primary Accession: Q01831
Other Accession: NP_001139241.1;NP_004619.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a component of the nucleotide excisionrepair (NER) pathway. There are multiple components involved in theNER pathway, including Xeroderma pigmentosum (XP) A-G and V,Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) groupA, etc. This component, XPC, plays an important role in the earlysteps of global genome NER, especially in damage recognition, opencomplex formation, and repair protein complex formation. Mutationsin this gene or some other NER components result in Xerodermapigmentosum, a rare autosomal recessive disorder characterized byincreased sensitivity to sunlight with the development ofcarcinomas at an early age. Alternatively spliced transcriptvariants have been found for this gene.
Other Names:
DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125, XPC, XPCC
Target/Specificity:
The synthetic peptide sequence is selected from aa 169-183 of HUMAN XPC
Gene Name: XPC
Gene ID: 7508
Primary Accession: Q01831
Other Accession: NP_001139241.1;NP_004619.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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