XPO1 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Alternative Name:
CRM1, Exportin-1, Exportin 1, Exportin1, Exp1

Application Dilution: WB: 1:500 - 1:2000

Specificity: XPO1 polyclonal antibody detects endogenous levels of XPO1 protein.

Immunogen:
A synthetic peptide of human XPO1.

MW: ~ 123 kDa

Swis Prot.: O14980

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.