XRCC1 (clone 3F6-G7-F7), anti-human

Background:
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents.This protein interacts with DNA ligase III,polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway.It may play a role in DNA processing during meiogenesis and recombination in germ cells.A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.[provided by RefSeq,Jul 2008]

Synonyms: RCC

Cellular Location: Nucleus

Immunogen:
Purified recombinant human XRCC1 protein fragments expressed in E.coli.

Gene Symbol: XRCC1

Gene ID: 7515

Swiss prot: P18887

Calculated MW: 82kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.