XRCC1 (clone 7B4C12), anti-

XRCC1 (clone 7B4C12), anti-

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In stock
SKU
BT-MCA3367
Catalog Number: BT-MCA3367
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity:
Application(s): WB, IHC, FCM
Datasheet
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Background:
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: RCC, SCAR26

Immunogen: Purified recombinant fragment of human XRCC1 (AA:1-150) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage
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