XRCC4 (clone 7C10) mouse monoclonal, anti-human, mouse, rat

Backgroud: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Synonyms: X ray repair cross complementing protein 4, DNA repair protein XRCC4, DNA double strand break repair

Gene Name: XRCC4

Gene ID: 7518

SwissProt ID: Q13426

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.