XRCC5 Antibody (Center K439) Blocking peptide
€363.00
In stock
SKU
AC-BP11960c
Background:
The protein encoded by this gene is the 80-kilodaltonsubunit of the Ku heterodimer protein which is also known asATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku isthe DNA-binding component of the DNA-dependent protein kinase, andit functions together with the DNA ligase IV-XRCC4 complex in therepair of DNA double-strand break by non-homologous end joining andthe completion of V(D)J recombination events. This genefunctionally complements Chinese hamster xrs-6, a mutant defectivein DNA double-strand break repair and in ability to undergo V(D)Jrecombination. A rare microsatellite polymorphism in this gene isassociated with cancer in patients of varying radiosensitivity.
Other Names:
X-ray repair cross-complementing protein 5, 364-, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, Ku80, Ku86, Lupus Ku autoantigen protein p86, Nuclear factor IV, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), XRCC5, G22P2
Gene Name: XRCC5
Gene ID: 7520
Primary Accession: P13010
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is the 80-kilodaltonsubunit of the Ku heterodimer protein which is also known asATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku isthe DNA-binding component of the DNA-dependent protein kinase, andit functions together with the DNA ligase IV-XRCC4 complex in therepair of DNA double-strand break by non-homologous end joining andthe completion of V(D)J recombination events. This genefunctionally complements Chinese hamster xrs-6, a mutant defectivein DNA double-strand break repair and in ability to undergo V(D)Jrecombination. A rare microsatellite polymorphism in this gene isassociated with cancer in patients of varying radiosensitivity.
Other Names:
X-ray repair cross-complementing protein 5, 364-, 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, Ku80, Ku86, Lupus Ku autoantigen protein p86, Nuclear factor IV, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), XRCC5, G22P2
Gene Name: XRCC5
Gene ID: 7520
Primary Accession: P13010
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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