XRCC5 (clone 5C5), anti-human, mouse
€0.00
In stock
SKU
BT-MCA2525
Catalog Number: BT-MCA2525
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human, mouse
Application(s): WB, IHC, ICC, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human, mouse
Application(s): WB, IHC, ICC, FCM
Datasheet
Request Information
Background:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Research Area: Epigenetics and Nuclear Signaling
Synonyms: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1, FLJ39089
Immunogen: Purified recombinant fragment of human XRCC5 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Research Area: Epigenetics and Nuclear Signaling
Synonyms: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1, FLJ39089
Immunogen: Purified recombinant fragment of human XRCC5 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
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