XRCC6 (clone 2F7F5), anti-human

XRCC6 (clone 2F7F5), anti-human

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In stock
SKU
BT-MCA2290
Catalog Number: BT-MCA2290
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, IHC, ICC, FCM
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Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: ML8, KU70, TLAA, CTC75, CTCBF, G22P1

Immunogen: Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage
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