XRN1 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP21479b
Background:
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Other Names:
5'-3' exoribonuclease 1, 3113-, Strand-exchange protein 1 homolog, XRN1, SEP1
Target/Specificity:
The synthetic peptide sequence is selected from aa 1389-1403 of HUMAN XRN1
Gene Name: XRN1 (HGNC:30654)
Gene ID: 54464
Primary Accession: Q8IZH2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Other Names:
5'-3' exoribonuclease 1, 3113-, Strand-exchange protein 1 homolog, XRN1, SEP1
Target/Specificity:
The synthetic peptide sequence is selected from aa 1389-1403 of HUMAN XRN1
Gene Name: XRN1 (HGNC:30654)
Gene ID: 54464
Primary Accession: Q8IZH2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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