ERCC1 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP69797
Background:
Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Other Names:
ERCC1; DNA excision repair protein ERCC-1
Antigen Type: synthetic peptide
Antigen Type: ERCC1
Gene ID: 2067
Primary Accession: P07992
Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Other Names:
ERCC1; DNA excision repair protein ERCC-1
Antigen Type: synthetic peptide
Antigen Type: ERCC1
Gene ID: 2067
Primary Accession: P07992
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