ZAK antibody (clone 3D11), anti-human
€435.00
In stock
SKU
AC-AT4567a
Catalog Number: AC-AT4567a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT4567a">Request Information
Background:
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
Mitogen-activated protein kinase kinase kinase MLT, Human cervical cancer suppressor gene 4 protein, HCCS-4, Leucine zipper- and sterile alpha motif-containing kinase, MLK-like mitogen-activated protein triple kinase, Mixed lineage kinase-related kinase, MLK-related kinase, MRK, Sterile alpha motif- and leucine zipper-containing kinase AZK, ZAK, MLTK
Antigen Type:
Recombinant Protein
Gene Name: MAP3K20 (HGNC:17797)
Gene ID: 51776
NCBI Accession: NP_057737.2;NP_598407.1
Primary Accession: Q9NYL2
Other Accession: BC001401
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Other Names:
Mitogen-activated protein kinase kinase kinase MLT, Human cervical cancer suppressor gene 4 protein, HCCS-4, Leucine zipper- and sterile alpha motif-containing kinase, MLK-like mitogen-activated protein triple kinase, Mixed lineage kinase-related kinase, MLK-related kinase, MRK, Sterile alpha motif- and leucine zipper-containing kinase AZK, ZAK, MLTK
Antigen Type:
Recombinant Protein
Gene Name: MAP3K20 (HGNC:17797)
Gene ID: 51776
NCBI Accession: NP_057737.2;NP_598407.1
Primary Accession: Q9NYL2
Other Accession: BC001401
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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