ZAP70 monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM2080a
Catalog Number: AC-AM2080a
Size: 100 µl
Isotype: mouse IgG1
Clone Name: 510CT8.1.2
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG1
Clone Name: 510CT8.1.2
Applications: WB
Datasheet
Request Information
Background:
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Other Names:
Tyrosine-protein kinase ZAP-70, 70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, ZAP70, SRK
Target/Specificity:
Purified His-tagged ZAP70 protein(Fragment) was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: ZAP70
Gene ID: 7535
Primary Accession: P43403
NCBI Accession: NP_001070.2;NP_997402.1
Other Accession: NP_001070.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Other Names:
Tyrosine-protein kinase ZAP-70, 70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, ZAP70, SRK
Target/Specificity:
Purified His-tagged ZAP70 protein(Fragment) was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: ZAP70
Gene ID: 7535
Primary Accession: P43403
NCBI Accession: NP_001070.2;NP_997402.1
Other Accession: NP_001070.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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