eIF2α monoclonal, anti-human
€470.00
In stock
SKU
AC-AP52859
Catalog Number: AC-AP55198
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
Datasheet
Request Information
Background:
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Other Names:
Dmel\CG6376 ;Dmel_CG6376 ;drosE2F1 ;E(Sev-CycE)3A ;E(var)3-93E ;E2-promoter binding facto ;E2F 1 ;E2F transcription factor 1 ;E2F-1 ;E2f-PA ;E2f-PB ;E2f-PC ;E2F1 ;E2f1 E2F transcription factor 1 ;E2F1_HUMAN ;Evar(3)164 ;KIAA4009 ;l(3)07172 ;l(3)j3B1 ;l(3)j3C2 ;l(3)rM729 ;mKIAA4009 ;OTTHUMP00000030661 ;PBR3 ;PRB binding protein E2F 1 ;PRB-binding protein E2F-1 ;RBAP 1 ;RBAP-1 ;RBAP1 ;RBBP-3 ;RBBP3 ;RBP 3 ;RBP3 ;Retinoblastoma-associated protein 1 ;Retinoblastoma-binding protein 3 ;Transcription factor E2F1.
Antigen Type: Recombinant Protein
Antigen Type: EIF2S1 (HGNC:3265)
Gene ID: 1965
Primary Accession: P05198
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Other Names:
Dmel\CG6376 ;Dmel_CG6376 ;drosE2F1 ;E(Sev-CycE)3A ;E(var)3-93E ;E2-promoter binding facto ;E2F 1 ;E2F transcription factor 1 ;E2F-1 ;E2f-PA ;E2f-PB ;E2f-PC ;E2F1 ;E2f1 E2F transcription factor 1 ;E2F1_HUMAN ;Evar(3)164 ;KIAA4009 ;l(3)07172 ;l(3)j3B1 ;l(3)j3C2 ;l(3)rM729 ;mKIAA4009 ;OTTHUMP00000030661 ;PBR3 ;PRB binding protein E2F 1 ;PRB-binding protein E2F-1 ;RBAP 1 ;RBAP-1 ;RBAP1 ;RBBP-3 ;RBBP3 ;RBP 3 ;RBP3 ;Retinoblastoma-associated protein 1 ;Retinoblastoma-binding protein 3 ;Transcription factor E2F1.
Antigen Type: Recombinant Protein
Antigen Type: EIF2S1 (HGNC:3265)
Gene ID: 1965
Primary Accession: P05198
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