ZBTB16 (clone 5B3), anti-human
€478.00
In stock
SKU
253036
Protein Family: Transcription factors
Pathway and Disease: Transcription
Description:
ZBTB16 (Zinc finger and BTB domain-containing protein 16) is a zinc finger transcription factor. It is a member of the Krueppel C2H2-type zinc-finger protein family, containing nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. It is expressed within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, at lower levels in the kidney and lung.
Alternate Names: Zinc finger and BTB domain-containing protein 16, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, Zinc finger protein PLZF, PLZF, ZNF145, ZBTB16
Application Notes: WB: 1:500-1:2000
Accession No.: Q05516
Antigen: Purified recombinant fragment of human ZBTB16 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Transcription
Description:
ZBTB16 (Zinc finger and BTB domain-containing protein 16) is a zinc finger transcription factor. It is a member of the Krueppel C2H2-type zinc-finger protein family, containing nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. It is expressed within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, at lower levels in the kidney and lung.
Alternate Names: Zinc finger and BTB domain-containing protein 16, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, Zinc finger protein PLZF, PLZF, ZNF145, ZBTB16
Application Notes: WB: 1:500-1:2000
Accession No.: Q05516
Antigen: Purified recombinant fragment of human ZBTB16 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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