ZC3H8 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5770
Background:
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (by similarity). ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Alternative Name:
Zinc finger CCCH domain-containing protein 8, ZC3HDC8
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ZC3H8 polyclonal antibody detects endogenous levels of ZC3H8 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 133-178 of Human ZC3H8.
MW: ~ 33 kDa
Swis Prot.: Q8N5P1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Zinc-finger CCCH domain-containing protein 8 (ZC3H8) acts as a transcriptional repressor of the GATA3 promoter. It is a sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (by similarity). ZC3H8 induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Alternative Name:
Zinc finger CCCH domain-containing protein 8, ZC3HDC8
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ZC3H8 polyclonal antibody detects endogenous levels of ZC3H8 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 133-178 of Human ZC3H8.
MW: ~ 33 kDa
Swis Prot.: Q8N5P1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review