ZCCHC17 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61229
Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson’s disease, Gaucher disease and Usher syndrome.
Alternative Name:
Nucleolar protein of 40 kDa, pNO40, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, PS1D protein, Zinc finger CCHC domain-containing protein 17, ZCCHC17, PS1D
Application Dilution: WB: 1:500~1:1000
Specificity: ZCCHC17 polyclonal antibody detects endogenous levels of ZCCHC17 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ZCCHC17.
MW: ~ 25 kDa
Swis Prot.: Q9NP64
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson’s disease, Gaucher disease and Usher syndrome.
Alternative Name:
Nucleolar protein of 40 kDa, pNO40, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, PS1D protein, Zinc finger CCHC domain-containing protein 17, ZCCHC17, PS1D
Application Dilution: WB: 1:500~1:1000
Specificity: ZCCHC17 polyclonal antibody detects endogenous levels of ZCCHC17 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ZCCHC17.
MW: ~ 25 kDa
Swis Prot.: Q9NP64
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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