ZKSCAN3 Blocking Peptide (N-Term)

Background:
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Other Names:
Zinc finger protein with KRAB and SCAN domains 3, Zinc finger and SCAN domain-containing protein 13, Zinc finger protein 306, Zinc finger protein 309, Zinc finger protein 47 homolog, Zf47, Zfp-47, ZKSCAN3, ZFP47, ZNF306, ZNF309, ZSCAN13

Target/Specificity:
The synthetic peptide sequence is selected from aa 120-130 of HUMAN ZKSCAN3

Gene Name: ZKSCAN3

Gene ID: 80317
Primary Accession: Q9BRR0
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.