ZKSCAN5 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61415
Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. A member of the Krüppel C2H2-type zinc-finger protein family, ZKSCAN5, also known as ZFP95, is a 839 amino acid protein containing thirteen C2H2-type zinc fingers, one KRAB A domain and one SCAN box domain. ZKSCAN5 is located in the nucleus and is highly expressed in testis with lower levels of expression in liver, kidney, brain, striated muscle, lung and heart. Many KRAB A box-containing proteins have been shown to function as transcription repressors, suggesting a possible function of ZKSCAN5. As a result of alternative splicing, three transcripts of ZKSCAN5 exist, however one of those transcripts is specific to testis. The mouse homolog of ZKSCAN5 is differentially expressed in spermatogenesis.
Alternative Name:
ZKSCAN5, Zfp-95, Zinc finger protein with KRAB and SCAN domains 5, Zinc finger protein 95 homolog, KIAA1015, ZFP95
Application Dilution: WB: 1:500~1:1000
Specificity: ZKSCAN5 polyclonal antibody detects endogenous levels of ZKSCAN5 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 284-329 of Human ZKSCAN5.
MW: ~ 96 kDa
Swis Prot.: Q9Y2L8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. A member of the Krüppel C2H2-type zinc-finger protein family, ZKSCAN5, also known as ZFP95, is a 839 amino acid protein containing thirteen C2H2-type zinc fingers, one KRAB A domain and one SCAN box domain. ZKSCAN5 is located in the nucleus and is highly expressed in testis with lower levels of expression in liver, kidney, brain, striated muscle, lung and heart. Many KRAB A box-containing proteins have been shown to function as transcription repressors, suggesting a possible function of ZKSCAN5. As a result of alternative splicing, three transcripts of ZKSCAN5 exist, however one of those transcripts is specific to testis. The mouse homolog of ZKSCAN5 is differentially expressed in spermatogenesis.
Alternative Name:
ZKSCAN5, Zfp-95, Zinc finger protein with KRAB and SCAN domains 5, Zinc finger protein 95 homolog, KIAA1015, ZFP95
Application Dilution: WB: 1:500~1:1000
Specificity: ZKSCAN5 polyclonal antibody detects endogenous levels of ZKSCAN5 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 284-329 of Human ZKSCAN5.
MW: ~ 96 kDa
Swis Prot.: Q9Y2L8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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