ZNF187 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5945
Background:
The best studied of the immediate early genes is the c-Fos proto-oncogene. Many of the signals inducing Fos expression act through a sequence located in the 5' flanking region of c-Fos, designated the serum response element (SRE). The SRE is required for response to activators of protein kinase C and Fos growth-induced signals independent of protein kinase C. Accumulating evidence argues that the SRE is a multifunctional element that may involve the action of multiple SRE-binding proteins. These include the serum response factor (SRF) and the two less well characterized proteins, TCF p62 and BBF p62. An SRE binding nuclear protein, designated SRE-ZBP, is a member of the C2H2 zinc finger family of proteins. Like c-Fos, SRE-ZBP is serum-inducible in HeLa cells, although with slower kinetics.
Alternative Name:
Zinc finger and SCAN domain-containing protein 26, Protein SRE-ZBP, Zinc finger protein 187, ZSCAN26
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: ZNF187 polyclonal antibody detects endogenous levels of ZNF187 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 149-194 of Human ZNF187.
MW: ~ 55 kDa
Swis Prot.: Q16670
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The best studied of the immediate early genes is the c-Fos proto-oncogene. Many of the signals inducing Fos expression act through a sequence located in the 5' flanking region of c-Fos, designated the serum response element (SRE). The SRE is required for response to activators of protein kinase C and Fos growth-induced signals independent of protein kinase C. Accumulating evidence argues that the SRE is a multifunctional element that may involve the action of multiple SRE-binding proteins. These include the serum response factor (SRF) and the two less well characterized proteins, TCF p62 and BBF p62. An SRE binding nuclear protein, designated SRE-ZBP, is a member of the C2H2 zinc finger family of proteins. Like c-Fos, SRE-ZBP is serum-inducible in HeLa cells, although with slower kinetics.
Alternative Name:
Zinc finger and SCAN domain-containing protein 26, Protein SRE-ZBP, Zinc finger protein 187, ZSCAN26
Application Dilution: WB: 1:500~1:1000, ICC: 1:50~1:200
Specificity: ZNF187 polyclonal antibody detects endogenous levels of ZNF187 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 149-194 of Human ZNF187.
MW: ~ 55 kDa
Swis Prot.: Q16670
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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