ZNF441 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60712
Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain several Krüppel-type DNA binding domains that are frequently observed to be involved in sequence-specific DNA binding. ZNF441 is a 626 amino acid transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. ZNF441 localizes to the nucleus and contains 19 C2H2-type zinc fingers. ZNF441 is encoded by a gene located on chromosome 19, which contains a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. Chromosome19 is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and FcR. Key genes for eye color and hair color also map to chromosome 19.
Alternative Name:
Zinc finger protein 441, ZNF441
Application Dilution: WB: 1:500~1:1000
Specificity: ZNF441 polyclonal antibody detects endogenous levels of ZNF441 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ZNF441
MW: ~ 80 kDa
Swis Prot.: Q8N8Z8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain several Krüppel-type DNA binding domains that are frequently observed to be involved in sequence-specific DNA binding. ZNF441 is a 626 amino acid transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. ZNF441 localizes to the nucleus and contains 19 C2H2-type zinc fingers. ZNF441 is encoded by a gene located on chromosome 19, which contains a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. Chromosome19 is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and FcR. Key genes for eye color and hair color also map to chromosome 19.
Alternative Name:
Zinc finger protein 441, ZNF441
Application Dilution: WB: 1:500~1:1000
Specificity: ZNF441 polyclonal antibody detects endogenous levels of ZNF441 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human ZNF441
MW: ~ 80 kDa
Swis Prot.: Q8N8Z8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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