ZNF460 polyclonal, anti-human, mouse, rat

Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF460 (zinc finger protein 460), also known as HZF8 or ZNF272, is a 562 amino acid nuclear protein that is ubiquitously expressed at low levels and expressed at high levels in pancreas and liver. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZNF460 contains 11 C2 H2-type zinc fingers and a KRAB domain. Like other zinc-fingers, ZNF460 is also suggested to be involved in transcriptional regulation.

Alternative Name:
Zinc finger protein 460, Zinc finger protein 272, Zinc finger protein HZF8, ZNF272

Application Dilution: WB: 1:500~1:1000

Specificity: ZNF460 polyclonal antibody detects endogenous levels of ZNF460 protein.

Immunogen:
Synthetic peptide, corresponding to amino acids 506-551 of Human ZNF460.

MW: ~ 64 kDa

Swis Prot.: Q14592

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.