ZNF50 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5985
Background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.
Alternative Name:
Zinc finger and SCAN domain-containing protein 22, Krueppel-related zinc finger protein 2, Protein HKR2, Zinc finger protein 50, ZSCAN22, HKR2
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ZNF50 polyclonal antibody detects endogenous levels of ZNF50 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 363-408 of Human ZNF50.
MW: ~ 55 kDa
Swis Prot.: P10073
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.
Alternative Name:
Zinc finger and SCAN domain-containing protein 22, Krueppel-related zinc finger protein 2, Protein HKR2, Zinc finger protein 50, ZSCAN22, HKR2
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ZNF50 polyclonal antibody detects endogenous levels of ZNF50 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 363-408 of Human ZNF50.
MW: ~ 55 kDa
Swis Prot.: P10073
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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