ZNRF2 monoclonal, anti-human, mouse, rat

Description: Anti-ZNRF2 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Protein Function:
May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates..

Other Names: E3 ubiquitin-protein ligase ZNRF2, 2.3.2.27, Protein Ells2, RING finger protein 202, RING-type E3 ubiquitin transferase ZNRF2, Zinc/RING finger protein 2, ZNRF2, RNF202

Clone Name(s):
Clone: IGB-26

Subcellular Localization: Endosome membrane ; Peripheral membrane protein. Lysosome membrane ; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane ; Peripheral membrane protein. Present in presynaptic plasma membranes in neurons.

Tissue Specificity: Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney..

Gene ID: 223082

Immunogen: A synthesized peptide derived from human ZNRF2

Calculated MW: 24115

Purification: Affinity-chromatography

Format: Liquid

Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.