ZnT-1 (R239) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS9171
Background:
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
Alternative Name:
Zinc transporter 1, ZnT-1, Solute carrier family 30 member 1, SLC30A1, ZNT1
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ZnT-1 (R239) polyclonal antibody detects endogenous levels of ZnT-1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 200-250 of Human ZnT-1.
MW: ~ 55 kDa
Swis Prot.: Q9Y6M5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
Alternative Name:
Zinc transporter 1, ZnT-1, Solute carrier family 30 member 1, SLC30A1, ZNT1
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: ZnT-1 (R239) polyclonal antibody detects endogenous levels of ZnT-1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 200-250 of Human ZnT-1.
MW: ~ 55 kDa
Swis Prot.: Q9Y6M5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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