ZO1 (clone ), anti-human, mouse, rat
€428.00
In stock
SKU
BS9802M
Background:
Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. ZO1 plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Alternative Name:
Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1, TJP1, ZO1
Application Dilution: ICC: 1:200, IHC: 1:200
Specificity: This antibody detects endogenous levels of ZO1 and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to ZO1.
MW: ~ 194 kDa
Swis Prot.: Q07157
Purification & Purity:
Peptide affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. ZO1 plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Alternative Name:
Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1, TJP1, ZO1
Application Dilution: ICC: 1:200, IHC: 1:200
Specificity: This antibody detects endogenous levels of ZO1 and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to ZO1.
MW: ~ 194 kDa
Swis Prot.: Q07157
Purification & Purity:
Peptide affinity purified
Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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