ZP4 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12724b
Background:
The zona pellucida is an extracellular matrix thatsurrounds the oocyte and early embryo. It is composed primarily ofthree or four glycoproteins with various functions duringfertilization and preimplantation development. The nascent proteincontains a N-terminal signal peptide sequence, a conserved ZPdomain, a consensus furin cleavage site, and a C-terminaltransmembrane domain. It is hypothesized that furin cleavageresults in release of the mature protein from the plasma membranefor subsequent incorporation into the zona pellucida matrix.However, the requirement for furin cleavage in this process remainscontroversial based on mouse studies. Previously, this gene hasbeen referred to as ZP1 or ZPB and thought to have similarfunctions as mouse Zp1. However, a human gene with highersimilarity and chromosomal synteny to mouse Zp1 has been assignedthe symbol ZP1 and this gene has been assigned the symbol ZP4.
Other Names:
Zona pellucida sperm-binding protein 4, Zona pellucida glycoprotein 4, Zp-4, Zona pellucida protein B, Processed zona pellucida sperm-binding protein 4, ZP4, ZPB
Gene Name: ZP4
Gene ID: 57829
Primary Accession: Q12836
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The zona pellucida is an extracellular matrix thatsurrounds the oocyte and early embryo. It is composed primarily ofthree or four glycoproteins with various functions duringfertilization and preimplantation development. The nascent proteincontains a N-terminal signal peptide sequence, a conserved ZPdomain, a consensus furin cleavage site, and a C-terminaltransmembrane domain. It is hypothesized that furin cleavageresults in release of the mature protein from the plasma membranefor subsequent incorporation into the zona pellucida matrix.However, the requirement for furin cleavage in this process remainscontroversial based on mouse studies. Previously, this gene hasbeen referred to as ZP1 or ZPB and thought to have similarfunctions as mouse Zp1. However, a human gene with highersimilarity and chromosomal synteny to mouse Zp1 has been assignedthe symbol ZP1 and this gene has been assigned the symbol ZP4.
Other Names:
Zona pellucida sperm-binding protein 4, Zona pellucida glycoprotein 4, Zp-4, Zona pellucida protein B, Processed zona pellucida sperm-binding protein 4, ZP4, ZPB
Gene Name: ZP4
Gene ID: 57829
Primary Accession: Q12836
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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