ZPK Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7214a
Background:
ZPK, a member of the Ser/Thr protein kinase family (MAP kinase kinase kinase subfamily), may be an activator of the JNK/SAPK pathway. It phosphorylates beta-casein, histone 1 and myelin basic protein in vitro, and interacts with MBIP through the leucine-zipper motif. ZPK is highly expressed in brain and kidney. It is phosphorylated in cytosol under basal conditions and dephosphorylated when membrane-associated.
Other Names:
Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase, MAP3K12, ZPK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7214a was selected from the C-term region of human ZPK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAP3K12
Gene ID: 7786
Primary Accession: Q12852
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
ZPK, a member of the Ser/Thr protein kinase family (MAP kinase kinase kinase subfamily), may be an activator of the JNK/SAPK pathway. It phosphorylates beta-casein, histone 1 and myelin basic protein in vitro, and interacts with MBIP through the leucine-zipper motif. ZPK is highly expressed in brain and kidney. It is phosphorylated in cytosol under basal conditions and dephosphorylated when membrane-associated.
Other Names:
Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase, MAP3K12, ZPK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7214a was selected from the C-term region of human ZPK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAP3K12
Gene ID: 7786
Primary Accession: Q12852
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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