α-SMA polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8796
Background:
Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Alternative Name:
ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: α-SMA polyclonal antibody detects endogenous levels of α-SMA protein.
Immunogen:
Recombinant full length Human α-SMA.
MW: ~ 42kDa
Swis Prot.: P62736
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Alternative Name:
ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, alpha-SMA, a-SMA, aSMA, SMA-alpha,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: α-SMA polyclonal antibody detects endogenous levels of α-SMA protein.
Immunogen:
Recombinant full length Human α-SMA.
MW: ~ 42kDa
Swis Prot.: P62736
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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