BANF1 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP14071c
Background:
The protein encoded by this gene was first identified byits ability to protect retroviruses from intramolecular integrationand therefore promote intermolecular integration into the host cellgenome. The protein forms a homodimer which localizes to both thenucleus and cytoplasm and is specifically associated withchromosomes during mitosis. This protein binds to double strandedDNA in a non-specific manner and also binds to LEM-domaincontaining proteins of the nuclear envelope. This protein isthought to facilitate nuclear reassembly by binding with both DNAand inner nuclear membrane proteins and thereby recruit chromatinto the nuclear periphery. Alternative splicing results in multipletranscript variants encoding the same protein.
Other Names:
Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor, N-terminally processed, BANF1, BAF, BCRG1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14071c was selected from the Center region of BANF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BANF1 {ECO:0000303|PubMed:21549337, ECO:0000312|HGNC:HGNC:17397}
Gene ID: 8815
Primary Accession: O75531
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene was first identified byits ability to protect retroviruses from intramolecular integrationand therefore promote intermolecular integration into the host cellgenome. The protein forms a homodimer which localizes to both thenucleus and cytoplasm and is specifically associated withchromosomes during mitosis. This protein binds to double strandedDNA in a non-specific manner and also binds to LEM-domaincontaining proteins of the nuclear envelope. This protein isthought to facilitate nuclear reassembly by binding with both DNAand inner nuclear membrane proteins and thereby recruit chromatinto the nuclear periphery. Alternative splicing results in multipletranscript variants encoding the same protein.
Other Names:
Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor, N-terminally processed, BANF1, BAF, BCRG1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14071c was selected from the Center region of BANF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BANF1 {ECO:0000303|PubMed:21549337, ECO:0000312|HGNC:HGNC:17397}
Gene ID: 8815
Primary Accession: O75531
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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