Bcl-w Antibody (BH3 Domain Specific) Blocking peptide
€363.00
In stock
SKU
AC-BP1305a
Background:
Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Other Names:
Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W, BCL2L2, BCLW, KIAA0271
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1305a was selected from the region of human Bcl-w BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BCL2L2
Gene ID: 599
Primary Accession: Q92843
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Other Names:
Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-W, BCL2L2, BCLW, KIAA0271
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1305a was selected from the region of human Bcl-w BH3 Domain. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: BCL2L2
Gene ID: 599
Primary Accession: Q92843
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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