C10orf2 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12799b
Background:
This gene encodes a hexameric DNA helicase which unwindsshort stretches of double-stranded DNA in the 5' to 3' directionand, along with mitochondrial single-stranded DNA binding proteinand mtDNA polymerase gamma, is thought to play a key role in mtDNAreplication. The protein localizes to the mitochondrial matrix andmitochondrial nucleoids. Mutations in this gene cause infantileonset spinocerebellar ataxia (IOSCA) and progressive externalophthalmoplegia (PEO) and are also associated with severalmitochondrial depletion syndromes. Alternative splicing results inmultiple transcript variants encoding distinct isoforms.
Other Names:
Twinkle protein, mitochondrial, Progressive external ophthalmoplegia 1 protein, T7 gp4-like protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase, PEO1, C10orf2
Gene Name: TWNK (HGNC:1160)
Gene ID: 56652
Primary Accession: Q96RR1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a hexameric DNA helicase which unwindsshort stretches of double-stranded DNA in the 5' to 3' directionand, along with mitochondrial single-stranded DNA binding proteinand mtDNA polymerase gamma, is thought to play a key role in mtDNAreplication. The protein localizes to the mitochondrial matrix andmitochondrial nucleoids. Mutations in this gene cause infantileonset spinocerebellar ataxia (IOSCA) and progressive externalophthalmoplegia (PEO) and are also associated with severalmitochondrial depletion syndromes. Alternative splicing results inmultiple transcript variants encoding distinct isoforms.
Other Names:
Twinkle protein, mitochondrial, Progressive external ophthalmoplegia 1 protein, T7 gp4-like protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase, PEO1, C10orf2
Gene Name: TWNK (HGNC:1160)
Gene ID: 56652
Primary Accession: Q96RR1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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