CCR5 Antibody(Center) Blocking peptide
€363.00
In stock
SKU
AC-BP19617c
Background:
This gene encodes a member of the beta chemokine receptorfamily, which is predicted to be a seven transmembrane proteinsimilar to G protein-coupled receptors. This protein is expressedby T cells and macrophages, and is known to be an importantco-receptor for macrophage-tropic virus, including HIV, to enterhost cells. Defective alleles of this gene have been associatedwith the HIV infection resistance. The ligands of this receptorinclude monocyte chemoattractant protein 2 (MCP-2), macrophageinflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatoryprotein 1 beta (MIP-1 beta) and regulated on activation normal Texpressed and secreted protein (RANTES). Expression of this genewas also detected in a promyeloblastic cell line, suggesting thatthis protein may play a role in granulocyte lineage proliferationand differentiation. This gene is located at the chemokine receptorgene cluster region. Two transcript variants encoding the sameprotein have been found for this gene.
Other Names:
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD195, CCR5, CMKBR5
Gene Name: CCR5 (HGNC:1606)
Gene ID: 1234
Primary Accession: P51681
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the beta chemokine receptorfamily, which is predicted to be a seven transmembrane proteinsimilar to G protein-coupled receptors. This protein is expressedby T cells and macrophages, and is known to be an importantco-receptor for macrophage-tropic virus, including HIV, to enterhost cells. Defective alleles of this gene have been associatedwith the HIV infection resistance. The ligands of this receptorinclude monocyte chemoattractant protein 2 (MCP-2), macrophageinflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatoryprotein 1 beta (MIP-1 beta) and regulated on activation normal Texpressed and secreted protein (RANTES). Expression of this genewas also detected in a promyeloblastic cell line, suggesting thatthis protein may play a role in granulocyte lineage proliferationand differentiation. This gene is located at the chemokine receptorgene cluster region. Two transcript variants encoding the sameprotein have been found for this gene.
Other Names:
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD195, CCR5, CMKBR5
Gene Name: CCR5 (HGNC:1606)
Gene ID: 1234
Primary Accession: P51681
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review