CCR8 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP10485b
Background:
CCR8 encodes a member of the beta chemokine receptorfamily, which is predicted to be a seven transmembrane proteinsimilar to G protein-coupled receptors. Chemokines and theirreceptors are important for the migration of various cell typesinto the inflammatory sites. This receptor protein preferentiallyexpresses in the thymus. I-309, thymus activation-regulatedcytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1beta) have been identified as ligands of this receptor. Studies ofthis receptor and its ligands suggested its role in regulation ofmonocyte chemotaxis and thymic cell apoptosis. More specifically,this receptor may contribute to the proper positioning of activatedT cells within the antigenic challenge sites and specialized areasof lymphoid tissues. CCR8 is located at the chemokine receptorgene cluster region.
Other Names:
C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
Gene Name: CCR8
Gene ID: 1237
Primary Accession: P51685
Other Accession: NP_005192.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CCR8 encodes a member of the beta chemokine receptorfamily, which is predicted to be a seven transmembrane proteinsimilar to G protein-coupled receptors. Chemokines and theirreceptors are important for the migration of various cell typesinto the inflammatory sites. This receptor protein preferentiallyexpresses in the thymus. I-309, thymus activation-regulatedcytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1beta) have been identified as ligands of this receptor. Studies ofthis receptor and its ligands suggested its role in regulation ofmonocyte chemotaxis and thymic cell apoptosis. More specifically,this receptor may contribute to the proper positioning of activatedT cells within the antigenic challenge sites and specialized areasof lymphoid tissues. CCR8 is located at the chemokine receptorgene cluster region.
Other Names:
C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
Gene Name: CCR8
Gene ID: 1237
Primary Accession: P51685
Other Accession: NP_005192.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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