CD105 Antibody (Center E395) Blocking Peptide
€363.00
In stock
SKU
AC-BP2880c
Background:
CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Other Names:
Endoglin, CD105, ENG, END
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2880c was selected from the Center region of human CD105. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ENG
Gene ID: 2022
Primary Accession: P17813
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Other Names:
Endoglin, CD105, ENG, END
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2880c was selected from the Center region of human CD105. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ENG
Gene ID: 2022
Primary Accession: P17813
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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