CD1A Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13538c
Background:
This gene encodes a member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene localizes to the plasma membrane and to recyclingvesicles of the early endocytic system. Alternatively splicedtranscript variants have been observed, but their biologicalvalidity has not been determined.
Other Names:
T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1a, CD1A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13538c was selected from the Center region of CD1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CD1A
Gene ID: 909
Primary Accession: P06126
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene localizes to the plasma membrane and to recyclingvesicles of the early endocytic system. Alternatively splicedtranscript variants have been observed, but their biologicalvalidity has not been determined.
Other Names:
T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1a, CD1A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13538c was selected from the Center region of CD1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CD1A
Gene ID: 909
Primary Accession: P06126
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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