CD1C polyclonal (C-term), anti-human
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In stock
SKU
AC-AP13430b
Catalog Number: AC-AP13430b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33845
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33845
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
Other Names:
T-cell surface glycoprotein CD1c, CD1c, CD1C
Target/Specificity:
This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C.
Antigen Region:
226-253
Antigen Type: Synthetic Peptide
Gene Name: CD1C
Gene ID: 911
Primary Accession: P29017
NCBI Accession: NP_001756.2
Other Accession: NP_001756.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
Other Names:
T-cell surface glycoprotein CD1c, CD1c, CD1C
Target/Specificity:
This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C.
Antigen Region:
226-253
Antigen Type: Synthetic Peptide
Gene Name: CD1C
Gene ID: 911
Primary Accession: P29017
NCBI Accession: NP_001756.2
Other Accession: NP_001756.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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