CD236 Polyclonal Antibody

Background:
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Research Area: Cancer, Cardiovascular

Synonyms:
CD236, CD236R, GE, GLPC, GLPC, Glycoconnectin, Glycophorin C (Gerbich blood group), Glycophorin D, Glycophorin-C, Glycophorin-D, Glycoprotein beta, GPC, GPD, Gypc, GYPD, MGC117309, MGC126191, MGC126192, PAS 2, PAS 2', PAS-2'', Sialoglycoprotein D

Immunogen: Recombinant protein of human GYPC

Swissprot: P04921
Gene Accession: BC104246

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-23809/sc-19458/sc-20629