CD68/CD68 (kpi) Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP17393c
Background:
This gene encodes a 110-kD transmembrane glycoprotein thatis highly expressed by human monocytes and tissue macrophages. Itis a member of the lysosomal/endosomal-associated membraneglycoprotein (LAMP) family. The protein primarily localizes tolysosomes and endosomes with a smaller fraction circulating to thecell surface. It is a type I integral membrane protein with aheavily glycosylated extracellular domain and binds to tissue- andorgan-specific lectins or selectins. The protein is also a memberof the scavenger receptor family. Scavenger receptors typicallyfunction to clear cellular debris, promote phagocytosis, andmediate the recruitment and activation of macrophages. Alternativesplicing results in multiple transcripts encoding differentisoforms.
Other Names:
Macrosialin, Gp110, CD68, CD68
Gene Name: CD68
Gene ID: 968
Primary Accession: P34810
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a 110-kD transmembrane glycoprotein thatis highly expressed by human monocytes and tissue macrophages. Itis a member of the lysosomal/endosomal-associated membraneglycoprotein (LAMP) family. The protein primarily localizes tolysosomes and endosomes with a smaller fraction circulating to thecell surface. It is a type I integral membrane protein with aheavily glycosylated extracellular domain and binds to tissue- andorgan-specific lectins or selectins. The protein is also a memberof the scavenger receptor family. Scavenger receptors typicallyfunction to clear cellular debris, promote phagocytosis, andmediate the recruitment and activation of macrophages. Alternativesplicing results in multiple transcripts encoding differentisoforms.
Other Names:
Macrosialin, Gp110, CD68, CD68
Gene Name: CD68
Gene ID: 968
Primary Accession: P34810
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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