CDK9 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13892b
Background:
The protein encoded by this gene is a member of thecyclin-dependent protein kinase (CDK) family. CDK family membersare highly similar to the gene products of S. cerevisiae cdc28, andS. pombe cdc2, and known as important cell cycle regulators. Thiskinase was found to be a component of the multiprotein complexTAK/P-TEFb, which is an elongation factor for RNA polymeraseII-directed transcription and functions by phosphorylating theC-terminal domain of the largest subunit of RNA polymerase II. Thisprotein forms a complex with and is regulated by its regulatorysubunit cyclin T or cyclin K. HIV-1 Tat protein was found tointeract with this protein and cyclin T, which suggested a possibleinvolvement of this protein in AIDS.
Other Names:
Cyclin-dependent kinase 9, C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit, CDK9, CDC2L4, TAK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13892b was selected from the C-term region of CDK9. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CDK9 {ECO:0000303|PubMed:10903437, ECO:0000312|HGNC:HGNC:1780}
Gene ID: 1025
Primary Accession: P50750
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of thecyclin-dependent protein kinase (CDK) family. CDK family membersare highly similar to the gene products of S. cerevisiae cdc28, andS. pombe cdc2, and known as important cell cycle regulators. Thiskinase was found to be a component of the multiprotein complexTAK/P-TEFb, which is an elongation factor for RNA polymeraseII-directed transcription and functions by phosphorylating theC-terminal domain of the largest subunit of RNA polymerase II. Thisprotein forms a complex with and is regulated by its regulatorysubunit cyclin T or cyclin K. HIV-1 Tat protein was found tointeract with this protein and cyclin T, which suggested a possibleinvolvement of this protein in AIDS.
Other Names:
Cyclin-dependent kinase 9, C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit, CDK9, CDC2L4, TAK
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13892b was selected from the C-term region of CDK9. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CDK9 {ECO:0000303|PubMed:10903437, ECO:0000312|HGNC:HGNC:1780}
Gene ID: 1025
Primary Accession: P50750
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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