CDKN2C Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP5520c
Background:
The protein encoded by this gene is a member of the INK4family of cyclin-dependent kinase inhibitors. This protein has beenshown to interact with CDK4 or CDK6, and prevent the activation ofthe CDK kinases, thus function as a cell growth regulator thatcontrols cell cycle G1 progression. Ectopic expression of this genewas shown to suppress the growth of human cells in a manner thatappears to correlate with the presence of a wild-type RB1 function.Studies in the knockout mice suggested the roles of this gene inregulating spermatogenesis, as well as in suppressingtumorigenesis. Two alternatively spliced transcript variants ofthis gene, which encode an identical protein, have been reported.
Other Names:
Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6
Gene Name: CDKN2C
Gene ID: 1031
Primary Accession: P42773
Other Accession: NP_523240
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of the INK4family of cyclin-dependent kinase inhibitors. This protein has beenshown to interact with CDK4 or CDK6, and prevent the activation ofthe CDK kinases, thus function as a cell growth regulator thatcontrols cell cycle G1 progression. Ectopic expression of this genewas shown to suppress the growth of human cells in a manner thatappears to correlate with the presence of a wild-type RB1 function.Studies in the knockout mice suggested the roles of this gene inregulating spermatogenesis, as well as in suppressingtumorigenesis. Two alternatively spliced transcript variants ofthis gene, which encode an identical protein, have been reported.
Other Names:
Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6
Gene Name: CDKN2C
Gene ID: 1031
Primary Accession: P42773
Other Accession: NP_523240
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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