CLCN7 polyclonal (C-term), anti-human

CLCN7 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP11863B
Catalog Number: AC-AP11863B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB31756
Applications: WB, IF, IHC-P
Datasheet

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Background:
The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Other Names:
H(+)/Cl(-) exchange transporter 7, Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, CLCN7

Target/Specificity:
This CLCN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-720 amino acids from the C-terminal region of human CLCN7.

Antigen Region:
692-720

Antigen Type: Synthetic Peptide

Gene Name: CLCN7 (HGNC:2025)
Gene ID: 1186
Primary Accession: P51798
NCBI Accession: NP_001107803.1;NP_001278.1
Other Accession: P51799; O70496; Q4PKH3; NP_001278.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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