COQ3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP8765c
Background:
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. COQ3 is an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Other Names:
Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial, 2-polyprenyl-6-hydroxyphenol methylase,4-dihydroxy-5-hexaprenylbenzoate methyltransferase, DHHB methyltransferase, DHHB-MT, DHHB-MTase, 3-demethylubiquinone-10 3-methyltransferase, Dihydroxyhexaprenylbenzoate methyltransferase, COQ3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8765c was selected from the Center region of human COQ3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: COQ3 {ECO:0000255|HAMAP-Rule:MF_03190}
Gene ID: 51805
Primary Accession: Q9NZJ6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. COQ3 is an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Other Names:
Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial, 2-polyprenyl-6-hydroxyphenol methylase,4-dihydroxy-5-hexaprenylbenzoate methyltransferase, DHHB methyltransferase, DHHB-MT, DHHB-MTase, 3-demethylubiquinone-10 3-methyltransferase, Dihydroxyhexaprenylbenzoate methyltransferase, COQ3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8765c was selected from the Center region of human COQ3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: COQ3 {ECO:0000255|HAMAP-Rule:MF_03190}
Gene ID: 51805
Primary Accession: Q9NZJ6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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