CTPS2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP8779a
Background:
CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.
Other Names:
CTP synthase 2, CTP synthetase 2, UTP--ammonia ligase 2, CTPS2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8779a was selected from the N-term region of human CTPS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CTPS2
Gene ID: 56474
Primary Accession: Q9NRF8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.
Other Names:
CTP synthase 2, CTP synthetase 2, UTP--ammonia ligase 2, CTPS2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8779a was selected from the N-term region of human CTPS2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CTPS2
Gene ID: 56474
Primary Accession: Q9NRF8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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