DBI polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7560
Background:
This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Alternative Name:
ACBD 1, ACBD1, ACBP, ACBP_HUMAN, Acyl CoA binding domain containing 1, Acyl CoA binding protein, Acyl Coenzyme A binding domain containing 1, acyl coenzyme A binding protein, Acyl-CoA-binding protein, acyl-Coenzyme A binding domain containing 1, CCK RP, CCKRP, Cholecystokinin releasing peptide trypsin sensitive, DBI, Diazepam-binding inhibitor, endozepine, EP, GABA receptor modulator acyl Coenzyme A binding protein, GABA receptor modulator, MGC70414,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: DBI polyclonal antibody detects endogenous levels of DBI protein.
Immunogen:
Recombinant full length Human DBI.
MW: ~10 kDa
Swis Prot.: P07108
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Alternative Name:
ACBD 1, ACBD1, ACBP, ACBP_HUMAN, Acyl CoA binding domain containing 1, Acyl CoA binding protein, Acyl Coenzyme A binding domain containing 1, acyl coenzyme A binding protein, Acyl-CoA-binding protein, acyl-Coenzyme A binding domain containing 1, CCK RP, CCKRP, Cholecystokinin releasing peptide trypsin sensitive, DBI, Diazepam-binding inhibitor, endozepine, EP, GABA receptor modulator acyl Coenzyme A binding protein, GABA receptor modulator, MGC70414,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: DBI polyclonal antibody detects endogenous levels of DBI protein.
Immunogen:
Recombinant full length Human DBI.
MW: ~10 kDa
Swis Prot.: P07108
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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